ASUS ESC4000A-E10 1-Socket 2U Accelerator Server with 4 GPU Support

ASUSSKU: ESC4000A-E10
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Description

The ASUS ESC4000A-E10 is a powerful 1-socket 2U accelerator server engineered to handle compute-intensive workloads with exceptional efficiency. Powered by 3rd Gen AMD EPYC™ processors with AMD 3D V-Cache™ technology, it delivers high core density and enhanced performance for AI, virtualization, and HPC applications—all within a thermally optimized chassis.

Designed for maximum GPU scalability, it supports up to four dual-slot PCIe 4.0 GPUs or eight single-slot GPUs, enabling unparalleled parallel processing capabilities. The server also features ASMB9-iKVM remote management, ASUS Control Center (ACC) for streamlined administration, and OCP 3.0 support for flexible networking expansion. With eight hot-swappable drive bays—including support for up to four NVMe drives—and redundant 80 PLUS Platinum power supplies, the ESC4000A-E10 ensures high availability and reliability for enterprise and data center environments.

Ideal for AI inference, cloud computing, streaming media, and virtualized workloads, this system combines performance, scalability, and intelligent management in a compact 2U form factor.

Category Specification
Processor 3rd Gen AMD EPYC™ 7003/7002 Series, up to 280W TDP with AMD 3D V-Cache™ technology
Form Factor 2U Rackmount Server
Memory 8 DIMM slots (8-channel per CPU); up to 2TB DDR4-3200 RDIMM
Expansion Slots 11x PCIe 4.0 slots (supports up to 4 double-deck or 8 single-wide GPUs)
OCP Slot 1x OCP 3.0 Gen 4.0 x16 Mezzanine slot
Storage Bays 8x 2.5"/3.5" hot-swap bays (up to 4x NVMe supported)
Networking 2x 1GbE (Intel® I350-AM2) + 1x dedicated management port
Graphics ASPEED AST2500, 64MB
Security TPM 2.0
Front I/O Ports 4x USB 3.0 ports
Rear I/O Ports 2x USB 3.0, 2x LAN (RJ45), 1x Management (RJ45), 1x VGA
Management ASUS Control Center (Classic), ASMB9-iKVM (KVM-over-IP)
Power Supply Options 1+1 Redundant 1600W or 2200W 80 PLUS Platinum
Dimensions (W x D x H) 440 x 800 x 88 mm (17.32" x 31.5" x 3.46")
Weight Net: 34 kg / Gross: 44 kg
Operating Temperature 10°C – 35°C
Supported OS Windows® Server 2019, RedHat®, SuSE®, Ubuntu®, VMware®
Target Applications AI / HPC / Virtualization / Cloud Computing / Streaming Media

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Return Policy (Short Summary)

We offer a 30-day return window for most unopened, factory-sealed items.

Returns must be authorized before shipping back and must include all original packaging and accessories. Opened or used items are not returnable unless defective.


Some products—such as custom orders, special-order items, audio gear, software, and LED video walls—are non-returnable. Non-defective returns may be subject to a 20–30% restocking fee, and customers are responsible for return shipping costs.


For damaged or incorrect items, please contact us immediately.


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01

Plan

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02

Engineer

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03

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04

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